Probably cation-transporter ATPase I CtpI, Mycobacterium tuberculosis.

Edit 2 …
Target (protein/gene name): Probable cation-transporter ATPase I CtpI
NCBI Gene # or RefSeq #: NC_000962.3
PBD ID: 3MD0
Organism: Mycobacterium tuberculosis
Etiologic Risk Group: Group 3
Links:
  1. http://www.bacterio.net/-hazard.html#group2
Disease Information:

Link to TDR Targets page (if present): N/A
Link to Gene Database page:
  1. http://www.uniprot.org/uniprot/A5TYI1
  2. https://www.patricbrc.org/view/Feature/RefSeq.1773.1200.CVMX01000008.CDS.107762.110716.rev
  3. https://www.ncbi.nlm.nih.gov/gene/886915

Essentiality of protein: essential; essentiality was unspecified
Complex of proteins:
Druggable target: 0.5 from TDR targets
Complex of proteins?:

Druggable Target (list number or cite evidence from a paper/database showing druggable in another organism):
EC #: 3.6.3.8
Link to BRENDA EC # page:
  1. 1. http://www.brenda-enzymes.org/enzyme.php?ecno=3.6.3.8#REACTION

Enzyme Assay: S-Nitrosoglutathione
SIGMA:
  • Cost: $177.00 for 25 mg/ $300.00 for 50 mg
  • Catalog #: N4148
  1. 1. https://www.sigmaaldrich.com/catalog/product/sigma/n4148?lang=en&region=US
  2. 2. https://www.scbt.com/scbt/product/s-nitrosoglutathione-gsno-57564-91-7
  3. 3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647110/

Structure (PDB): 3MD0
Current Inhibitors: http://www.brenda-enzymes.org/enzyme.php?ecno=3.6.3.8#INHIBITORS
Expression Information (has it been expressed in bacterial cells): N/A
Purification Method: deoxycholate and salt fractionation
  1. 1. http://www.jbc.org/content/245/17/4508.full.pdf

Image of protein:


Amino acid sequence:


Length of protein in amino acids: 1632 aa
Molecular weight of protein: 169.61 kDa
Molar Extinction coefficient (280 nm wavelength): 128910 M-1cm-1
TMpred graph image: